Lake Como, Italy
Located in northern Italy's Lombardy region, this upscale destination is known for its famous waterfront villas — George Clooney, Sting, Madonna, Donatella Versace and Sir Richard Branson all own or have owned villas here.
Get a slightly less permanent taste of luxury at Villa Carlotta, a villa that has been turned into an art museum and botanical garden. And if you really want to splurge, stay at the CastaDiva Resort & SPA, a 5-star hotel right on the lake.
[Photo via @explorelakecomo]