Blue Ridge Parkway, VA/NC
If you're less into fall activities and more interested in taking in the fall foliage, it's time to take a scenic fall road-trip through the Blue Ridge Parkway, which runs through parts of Virginia and North Carolina. Named "America's favorite drive," this 469 mile parkway offers some of the best and most colorful views in the region.
More info here.
[Photo via @nicksters_21]