Réunion Bar
Escape the work environment (and the Manhattan environment) and enter the (almost) tropical paradise that is Réunion Bar. They can't bring you to the beach, but they can bring you Taco Tuesday and Hawaiian Hump Day. If two days aren't enough, they offer happy hour specials on shots, cocktails, beers, and bar food ranging from $3-$6 on Monday, Thursday, and Friday. Try the Acid Drop shot if you've had an especially rough day at the office.
Réunion Bar, NE corner of 44th & 9th, 212-582-3200
[Photo via @prof_mcintyre]